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Article

Prepro-endothelin-1 mRNA and its mature peptide in human appendix.

American journal of physiology. Gastrointestinal and liver physiology - 1 Feb 2003

Massai Lauretta, Carbotti Paola, Cambiaggi Caterina, Mencarelli Marzia, Migliaccio Pierluigi, Muscettola Michela, Grasso Giovanni

Abstract excerpt

Because the precise immunopathological events occurring in appendicitis are not completely understood, possible local production of endothelin-1 (ET-1) in human appendix was investigated. We used immunohistochemistry and in situ hybridization to detect the presence, distribution, and phenotype of ET-1-positive cells and prepro-ET-1 (pp-ET-1) mRNA-expressing cells. ET-1-positive stromal cells and pp-ET-1...

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PMID: 12529269
DOI: 10.1152/ajpgi.00262.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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