Article
Studying cancer families to identify kidney cancer genes.
Annual review of medicine - 1 Jan 2003
Zbar Berton, Klausner Richard, Linehan W Marston
Abstract excerpt
We studied families with multiple members affected with renal cancer to delineate clinically distinct forms of inherited renal cancer, and to identify and characterize the genes responsible for these disorders. Today, cancer geneticists recognize seven clinically distinct, inherited forms of epithelial renal cancer; genes responsible for five inherited predispositions have been found. Positional cloning efforts...
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