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Article

Association of the hormone sensitive lipase -60C > G variant with fasting insulin levels in healthy young men.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Aug 2002

Talmud P J, Palmen J, Nicaud V, Tiret L

Abstract excerpt

BACKGROUND AND AIM: Hormone sensitive lipase (HSL) is the rate-limiting enzyme in triglyceride intracellular lipolysis, generating free fatty acids for energy utilisation. HSL is also expressed in pancreatic beta-cells where its activity may affect insulin secretion. We previously identified an HSL promoter variant, -60C > G, which in vitro exhibits 40% reduced promoter activity. METHODS AND RESULTS: In this...

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PMID: 12514936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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