Article
[Association of the relationship between HLA-DQB1 alleles and major beta-thalassemia in 42 guangdong Chinese].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2002
Bao Rong, Chen Chun, Fang Jian-Pei, Huang Shao-Liang
Abstract excerpt
To investigate the relationship between HLA-DQB1* alleles and major beta-thalassemia, the HLA-DQB1* loci typing was performed with polymerase chain reaction-sequence specific primer (PCR-SSP) in 42 unrelated (unconsanguineous) patients with major beta-thalassemia and 45 normal control individuals in Guangdong Province. Results showed that the frequency of HLA-DQB1*06 allele in patient group (19.0%) was higher...
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