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Article

Yield of screening for CADASIL mutations in lacunar stroke and leukoaraiosis.

Stroke - 1 Jan 2003

Dong Yanbin, Hassan Ahamad, Zhang Zhongyi, Huber Dionne, Dalageorgou Chrysoula, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic disorder typified by early onset lacunar strokes, subcortical dementia, psychiatric disturbances, and migraine. Mutations in the Notch3 gene are responsible. Atypical phenotypes have been recognized, and the disease is probably underdiagnosed in the wider stroke population....

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Source

Identifiers

PMID: 12511775
DOI: 10.1161/01.str.0000048162.16852.88

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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