Isolation of a negative control mutant of the nitrogen assimilation control protein, NAC, in Klebsiella aerogenes.

Abstract excerpt

A negative control mutant of the nitrogen assimilation control protein, NAC, has been isolated. Mutants with the leucine at position 111 changed to a nonhydrophobic residue activate transcription from hut and ure promoters, but fail to repress gdhA expression. This failure does not result from failure to bind to either of the two sites required for gdhA repression, but the binding at those sites is altered in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Enzyme Repression
• Share to Gene Expression Regulation, Bacterial