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Article

Transgenesis applied to transmissible spongiform encephalopathies.

Transgenic research - 1 Dec 2002

Vilotte Jean-Luc, Laude Hubert

Abstract excerpt

Transmissible spongiform encephalopathies (TSE) are fatal neurodegenerative disorders present in various mammals. TSEs have been studies intensively, even more so following the BSE crisis and the subsequent threat of a human nvCJD epidemic. In the 'protein-only' hypothesis, the infectious agent, called prion, is assumed to be a misfolded host protein. Transgenesis has mainly been applied to study the role of this...

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PMID: 12509129
DOI: 10.1023/a:1021125510220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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