Article
Predictive value of provirus load and DNA human immunodeficiency virus genotype for successful abacavir-based simplified therapy.
The Journal of infectious diseases - 1 Jan 2003
Pellegrin Isabelle, Caumont Anne, Garrigue Isabelle, Merel Patrick, Schrive Marie-Hélène, Fleury Hervé, Dupon Michel, Pellegrin Jean-Luc, Ragnaud Jean-Marie
Abstract excerpt
Of 75 human immunodeficiency virus (HIV) type 1-infected patients successfully responding to 2 nucleoside reverse-transcriptase inhibitors (NRTIs) plus 1 protease inhibitor (PI), 55 started a simplified abacavir (ABC)-based triple NRTI regimen. Influences of DNA load and DNA reverse-transcriptase (RT) mutations on virological responses were assessed at month 6 after initiation of therapy. Baseline heterogeneity...
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