The infection staging and profile of genotypic distribution and drug resistance mutation among the human immunodeficiency virus-1 infected blood donors from five Chinese blood centers, 2012-2014.

doi:10.1371/journal.pone.0179328

Article

The infection staging and profile of genotypic distribution and drug resistance mutation among the human immunodeficiency virus-1 infected blood donors from five Chinese blood centers, 2012-2014.

PloS one - 1 Jan 2017

Zeng Peibin, Liu Yu, He Miao, Wang Jingxing, Keating Sheila, Mao Wei, Huang Mei, Ma Hongli, He Weilan, Bi Xinhong, Liao Dan, Busch Michael, Ness Paul, Liu Jing, Shan Hua

Abstract excerpt

The increasing complexity and diversity of the human immunodeficiency virus-1 (HIV-1) infections challenge the disease control and anti-retrovirus treatment in China. The infection stages and molecular characteristics of HIV-1 from infected Chinese blood donors were examined to shed light on the HIV genotype distribution and the status of drug resistance mutations (DRMs) in the changing HIV epidemic in China....

Topics

Adolescent
Adult
Asian People
Blood Banks
Blood Donors
China
Drug Resistance, Viral
Female
Genotype
HIV Infections

HIV Protease

HIV Protease Inhibitors

HIV Reverse Transcriptase

HIV-1

Humans

Male

Middle Aged

Mutation

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