Article
HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir.
AIDS (London, England) - 13 Apr 2001
Lanier E R, Sturge G, McClernon D, Brown S, Halman M, Sacktor N, McArthur J, Atkinson J H, Clifford D, Price R W, Simpson D, Torres G, Catalan J, Marder K, Power C, Hall C, Romero C, Brew B
Abstract excerpt
OBJECTIVE: To assess HIV-1 RNA levels and the relationship between HIV-1 reverse transcriptase (RT) genotype from plasma and cerebrospinal fluid (CSF) during treatment with abacavir (Ziagen, ABC) or placebo in combination with stable background therapy (SBG) in subjects with AIDS dementia complex (ADC) (study CNA3001). DESIGN: One-hundred and five HIV-1 infected adults with ADC were randomized to receive either...
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