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Comparative genomic hybridisation divides retinoblastomas into a high and a low level chromosomal instability group

23 Dec 2002

Abstract excerpt

BACKGROUND: Retinoblastoma is the most common intraocular malignancy in childhood and is responsible for approximately 1% of all deaths caused by childhood cancer. AIMS/METHODS: Comparative genomic hybridisation was performed on 13 consecutive, histologically confirmed retinoblastomas to analyse patterns of chromosomal changes and correlate these to clinicopathological variables. Six cases were hereditary and...

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PMID: 12499428
DOI: 10.1136/jcp.56.1.26

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