Article
Transgenic swine for biomedicine and agriculture.
Theriogenology - 1 Jan 2003
Prather R S, Hawley R J, Carter D B, Lai L, Greenstein J L
Abstract excerpt
Initial technologies for creating transgenic swine only permitted random integration of the construct. However, by combining the technology for homologous recombination in fetal somatic cells with that of nuclear transfer (NT), it is now possible to create specific modifications to the swine genome. The first such example is that of knocking out a gene that is responsible for hyperacute rejection (HAR) when...
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