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Article

Peroxisome proliferator-activated receptor gamma activation induces cell cycle arrest via the p53-independent pathway in human anaplastic thyroid cancer cells.

Japanese journal of cancer research : Gann - 1 Dec 2002

Chung Sung Hwa, Onoda Naoyoshi, Ishikawa Tetsuro, Ogisawa Kana, Takenaka Chiemi, Yano Yoshihisa, Hato Fumihiko, Hirakawa Kosei

Abstract excerpt

Anaplastic thyroid carcinoma is one of the most aggressive human malignancies. Outcomes of intensive multimodal therapy have been far from satisfactory. Furthermore, p53 gene dysfunction, often found in this type of cancer, is known to impair the efficacy of the therapeutic agents. Specific ligan...

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Identifiers

PMID: 12495476
DOI: 10.1111/j.1349-7006.2002.tb01245.x
PMCID: PMC5926938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12495476-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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