An outbreak of a CTX-M-type beta-lactamase-producing Klebsiella pneumoniae: the importance of using cefpodoxime to detect extended-spectrum beta-lactamases

Abstract excerpt

Sir, CTX-M-type β-lactamases are similar to other extended-spectrum β-lactamases (ESBLs) in that they hydrolyse broad-spectrum cephalosporins and aztreonam. The CTX-M-type β-lactamases differ, however, from other ESBLs in acting primarily as cefotaximases. Although there is an increasing incidence of CTX-M β-lactamases worldwide1 they have not yet been reported in the UK. We describe our preliminary findings from...

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