Disc methods for detecting AmpC β-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae

Abstract excerpt

Sir, The increasing prevalence of AmpC β-lactamase-mediated resistance among Escherichia coli and Klebsiella pneumoniae is of clinical concern.1 Both of these organisms can acquire AmpC β-lactamases on plasmids and additionally, E. coli can hyper-produce its chromosomal AmpC β-lactamase, which is normally only produced at very low levels.2 The recognition of AmpC β-lactamase producers can be difficult, although...

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