Prognostic impact of cytogenetic and interphase fluorescence <i>in situ</i> hybridization‐defined chromosome 13 deletion in multiple myeloma: early results of total therapy II

Abstract excerpt

Cytogenetic abnormalities of chromosome 13 (CA 13) and those detected by fluorescence in situ hybridization (FISH 13) have both been associated with poor prognosis in multiple myeloma (MM) patients. The prognostic implications of CA, FISH 13 and other standard laboratory parameters were examined in the first 231 patients enrolled in Total Therapy II, an intensive cytotoxic chemotherapy programme with tandem...

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