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Article

The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene.

The Journal of biological chemistry - 18 Apr 2003

Nowling Tamara, Bernadt Cory, Johnson Lance, Desler Michelle, Rizzino Angie

Abstract excerpt

Distal enhancers commonly regulate gene expression. However, the mechanisms of transcriptional mediation by distal enhancers remain largely unknown. To better understand distal enhancer-mediated transcription, we examined the regulation of the FGF-4 gene. The FGF-4 gene is regulated during early development by a powerful distal enhancer located downstream of the promoter in exon 3. Sox-2 and Oct-3 bind to the...

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Identifiers

PMID: 12488456
DOI: 10.1074/jbc.M207567200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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