Article
Clinicopathologic significance of structural alterations of p53 protein in papillary thyroid carcinoma.
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Jun 2002
Chen Yifeng, Zhang Pengfei, Li Yiwei, Zhuang Jianliang, Gao Lingyun
Abstract excerpt
OBJECTIVE: To make a thorough study on the clinicopathologic significance of the three-dimensional structural alteration of the p53 protein in papillary thyroid carcinomas and to provide an objective criterion for the evaluation of PTC prognosis. METHODS: A total of 41 PTC cases were enrolled. Techniques including polymerase chain reaction with single strand conformational polymorphism (PCR-SSCP), DNA sequencing,...
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