Article
Equine herpesvirus 1 mutants devoid of glycoprotein B or M are apathogenic for mice but induce protection against challenge infection.
Virology - 8 Dec 1997
Neubauer A, Beer M, Brandmüller C, Kaaden O R, Osterrieder N
Abstract excerpt
Equine herpesvirus 1 (EHV-1) mutants devoid of the open reading frames (ORFs) of either glycoprotein (g) B or M were constructed and tested for their immunogenic potential in a murine model of EHV-1 infection. The mutant viruses were engineered using the virulent EHV-1 strain RacL11 or the modified live vaccine strain RacH by inserting the Escherichia coli LacZ gene into the viral ORFs. RacL11-infected mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
