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Asymmetric Cell Kinetics Genes: The Key to Expansion of Adult Stem Cells in Culture

1 Nov 2002

Abstract excerpt

A singular challenge in stem cell research today is the expansion and propagation of functional adult stem cells. Unlike embryonic stem cells, which are immortal in culture, adult stem cells are notorious for the difficulty encountered when attempts are made to expand them in culture. One overlooked reason for this difficulty may be the inherent asymmetric cell kinetics of stem cells in postnatal somatic tissues....

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PMID: 12456964
DOI: 10.1634/stemcells.20-6-561

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