Article
The mold-specific MS8 gene is required for normal hypha formation in the dimorphic pathogenic fungus Histoplasma capsulatum.
Eukaryotic cell - 1 Apr 2002
Tian Xianbin, Shearer Glenmore
Abstract excerpt
The dimorphic fungus Histoplasma capsulatum is the etiologic agent of one of the most common systemic mycoses of humans, histoplasmosis. In the environment, H. capsulatum grows in a differentiated mold form and shifts to an undifferentiated yeast form after mold fragments or spores are inhaled. This mold-to-yeast shift is required for disease. Little is known about the molecular biology of dimorphism in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
