Article
Assessment of hemagglutinin sequence heterogeneity during influenza virus transmission in families.
The Journal of infectious diseases - 1 Dec 2002
Gubareva Larisa V, Novikov Dmitri V, Hayden Frederick G
Abstract excerpt
To examine the molecular epidemiology of influenza virus transmission, the nucleotide sequences of the HA1 domain of the hemagglutinin (HA) gene of 57 influenza A and 24 influenza B viruses recovered in a single season were analyzed. No nucleotide sequence differences were found among the 10 viruses that were recovered twice from the same patient. The nucleotide sequences of influenza A viruses were identical...
Topics
- Adolescent
- Adult
- Amino Acid Sequence
- Child
- Child, Preschool
- Family Characteristics
- Female
- Genetic Variation
- Hemagglutinin Glycoproteins, Influenza Virus
- Humans
- Infant
- Influenza A virus
- Influenza B virus
- Influenza, Human
- Male
- Middle Aged
- Molecular Epidemiology
- Molecular Sequence Data