Article
Genetic variation and evolution of human parainfluenza virus type 1 hemagglutinin neuraminidase: analysis of 12 clinical isolates.
The Journal of infectious diseases - 1 Nov 1992
Henrickson K J, Savatski L L
Abstract excerpt
The extent of genetic variation and evolution in a population of human parainfluenza virus type 1 was investigated. The hemagglutinin neuraminidase genes of 13 isolates collected over a 26-year period were sequenced and compared. All isolates except the 1957 type strain were from a single geographic location and demonstrated significant consistent genetic change from the type strain (47/7 [nucleotide/amino acid]...
Topics
- Animals
- Base Sequence
- Biological Evolution
- Cell Line
- Genes, Viral
- Genetic Variation
- Haplorhini
- Hemagglutinins, Viral
- Humans
- Molecular Sequence Data
- Neuraminidase
