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Article

Association of interleukin-1 receptor antagonist gene polymorphisms with early onset periodontitis in Japanese.

Journal of clinical periodontology - 1 Oct 2002

Tai Hideaki, Endo Motohiro, Shimada Yasuko, Gou Emire, Orima Kazuko, Kobayashi Tetsuo, Yamazaki Kazuhisa, Yoshie Hiromasa

Abstract excerpt

BACKGROUND/AIMS: Early onset periodontitis (EOP), newly 'aggressive periodontitis', is considered to have genetic basis, which have not been clearly defined. The interleukin-1 (IL-1) gene cluster polymorphism as one of genetic factors may influence the expression of several chronic inflammatory diseases. The aim of this study is to investigate the frequency of single nucleotide polymorphisms (SNPs) in the genes...

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Identifiers

PMID: 12445219
DOI: 10.1034/j.1600-051x.2002.291002.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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