Article
KCNQ1 and KCNH2 mutations associated with long QT syndrome in a Chinese population.
Human mutation - 1 Dec 2002
Liu Wenling, Yang Junguo, Hu Dayi, Kang Cailian, Li Cuilan, Zhang Shuoyan, Li Ping, Chen Zhijian, Qin Xuguang, Ying Kang, Li Yuntian, Li Yushu, Li Zhiming, Cheng Xin, Li Lei, Qi Yu, Chen Shenghan, Wang Qing
Abstract excerpt
The long QT syndrome (LQTS) is a cardiac disorder characterized by prolongation of the QT interval on electrocardiograms (ECGs), syncope and sudden death caused by a specific ventricular tachyarrhythmia known as torsade de pointes. LQTS is caused by mutations in ion channel genes including the cardiac sodium channel gene SCN5A, and potassium channel subunit genes KCNQ1, KCNH2, KCNE1, and KCNE2. Little information...
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