Article
Primordial genetics: phenotype of the ribocyte.
Annual review of genetics - 1 Jan 2002
Yarus Michael
Abstract excerpt
The idea that the ancestors of modern cells were RNA cells (ribocytes) can be investigated by asking whether all essential cellular functions might be performed by RNAs. This requires isolating suitable molecules by selection-amplification when the predicted molecules are presently extinct. In fact, RNAs with many properties required during a period in which RNA was the major macromolecular agent in cells (an RNA...
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