Article
Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.
Journal of virology - 1 Dec 2002
Dvorin Jeffrey D, Bell Peter, Maul Gerd G, Yamashita Masahiro, Emerman Michael, Malim Michael H
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) can infect nondividing cells productively because the nuclear import of viral nucleic acids occurs in the absence of cell division. A number of viral factors that are present in HIV-1 preintegration complexes (PICs) have been assigned functions in nucle...
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