Article
Effect of chondroitin sulfate on murine splenocytes sensitized with ovalbumin.
Immunology letters - 3 Dec 2002
Sakai Shinobu, Akiyama Hiroshi, Harikai Naoki, Toyoda Hidenao, Toida Toshihiko, Maitani Tamio, Imanari Toshio
Abstract excerpt
Chondroitin sulfate (CS) is a glycosaminoglycan that is widely present in animals organisms, and it has anti-inflammatory and chondroprotective properties. To examine the effects of CS on the immune system, splenocytes obtained from ovalbumin (OVA)-sensitized BALB/c mice were challenged with OVA in the presence of CS, and cytokine levels in the medium of the cultured cells were measured. CS induced secretion of...
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