Article
Bilateral periventricular nodular heterotopia due to filamin 1 gene mutation: widespread glomeruloid microvascular anomaly and dysplastic cytoarchitecture in the cerebral cortex.
Acta neuropathologica - 1 Dec 2002
Kakita Akiyoshi, Hayashi Shintaro, Moro Francesca, Guerrini Renzo, Ozawa Tsunenori, Ono Koji, Kameyama Shigeki, Walsh Christopher A, Takahashi Hitoshi
Abstract excerpt
Bilateral periventricular nodular heterotopia (BPNH) is a neuronal migration disorder that is characterized by subependymal nodules of gray matter. Recently, a causative gene for BPNH, filamin 1, has been identified, and possible roles of the translated protein in cell migration and blood vessel development have been proposed. We report here the histopathological features of an autopsy case of BPNH with...
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