Article
Norepinephrine transporter gene (NET) variants in patients with panic disorder.
Neuroscience letters - 15 Nov 2002
Sand P G, Mori T, Godau C, Stöber G, Flachenecker P, Franke P, Nöthen M M, Fritze J, Maier W, Lesch K-P, Riederer P, Beckmann H, Deckert J
Abstract excerpt
Several lines of evidence suggest that catecholamines, especially norepinephrine, are implicated in the etiology and/or symptomatology of panic disorder (PD). At the cellular level, functional noradrenergic neurotransmission depends on synaptic reuptake of norepinephrine as mediated by the norepinephrine transporter (NET). A pharmacological target of agents with an established anti-panic efficacy, e.g. tricyclic...
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