Article
Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration.
Development (Cambridge, England) - 1 Nov 2002
Poss Kenneth D, Nechiporuk Alex, Hillam Ann M, Johnson Stephen L, Keating Mark T
Abstract excerpt
One possible reason why regeneration remains enigmatic is that the dominant organisms used for studying regeneration are not amenable to genetic approaches. We mutagenized zebrafish and screened for temperature-sensitive defects in adult fin regeneration. The nightcap mutant showed a defect in fin regeneration that was first apparent at the onset of regenerative outgrowth. Positional cloning revealed that...
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