Article
fgf20 is essential for initiating zebrafish fin regeneration.
Science (New York, N.Y.) - 23 Dec 2005
Whitehead Geoffrey G, Makino Shinji, Lien Ching-Ling, Keating Mark T
Abstract excerpt
Epimorphic regeneration requires the presence or creation of pluripotent cells capable of reproducing lost organs. Zebrafish fin regeneration is mediated by the creation of blastema cells. Here, we characterize the devoid of blastema (dob) mutant that fails fin regeneration during initial steps, forms abnormal regeneration epithelium, and does not form blastema. This mutation has no impact on embryonic survival....
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