Article
Analyses of serum lipoprotein(a) and the relation to phenotypes and genotypes of apolipoprotein(a) in type 2 diabetic patients with retinopathy.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Oct 2002
Suehiro M, Ohkubo K, Kato H, Kido Y, Anzai K, Oshima K, Ono J
Abstract excerpt
To elucidate the association of lipoprotein(a) (Lp(a)) with diabetic retinopathy (DR), we studied the serum Lp(a) concentrations (n = 412), apolipoprotein(a) (apo(a)) phenotypes expressed by the number of kringle 4 (K4) repeats (n = 150), apo(a) gene genotypes (n = 161) of type 2 diabetes with or without DR. The 5'-untranslated region of apo(a) gene was classified into seven haplotypes (A to G) and 18 genotypes...
Topics
- 5' Untranslated Regions
- Adult
- Aged
- Aged, 80 and over
- Apolipoproteins
- Apoprotein(a)
- Diabetes Mellitus, Type 2
- Diabetic Retinopathy
- Female
- Genotype