Article
Induction of the soxRS regulon of Escherichia coli by glycolaldehyde.
Archives of biochemistry and biophysics - 1 Nov 2002
Benov Ludmil, Fridovich Irwin
Abstract excerpt
The ability of short-chain sugars to cause oxidative stress has been examined using glycolaldehyde as the simplest sugar. Short-chain sugars autoxidize in air, producing superoxide and alpha,beta-dicarbonyls. In Escherichia coli the soxRS regulon mediates an oxidative stress response, which protects the cell against both superoxide-generating agents and nitric oxide. In superoxide dismutase-deficient E. coli...
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