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Article

[Molecular study of the BRCA1 and BRCA2 genes in 153 breast cancer families from Castilla and León (Spain): new nine unclassified variants identified].

Medicina clinica - 12 Oct 2002

Velasco Sampedro Eladio, Esteban Cardeñosa Eva, Infante Sanz Mar, Durán Domínguez Mercedes, Lastra Aras Enrique, García Girón Carlos, Miner Pino Cristina

Abstract excerpt

BACKGROUND: It is estimated that 5-10% of breast cancers have an hereditary origin, germline mutations of BRCA1 and BRCA2 genes causing a predisposition. In the present study we analyzed BRCA1 and BRCA2 mutations in moderate to high risk breast cancer patients in order to find out the types and frequency of these mutations in the Spanish regional community of Castilla y León. PATIENTS AND METHOD: We studied 207...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12385650
DOI: 10.1016/s0025-7753(02)73450-7

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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