Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction and expression of betaig-h3 in pancreatic cancer cells.

Biochimica et biophysica acta - 9 Oct 2002

Schneider Dominik, Kleeff Jörg, Berberat Pascal O, Zhu Zhaowen, Korc Murray, Friess Helmut, Büchler Markus W

Abstract excerpt

betaig-h3 (TGFBI, keratoepithelin) was first identified as a transforming growth factor-beta1 (TGF-beta1)-inducible gene in a human lung adenocarcinoma cell line. It encodes for a secreted extracellular matrix (ECM) protein, which is thought to act on cell attachment and ECM composition. Mutations of the betaig-h3 gene are involved in several corneal dystrophies. Pancreatic cancers display multiple alterations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Transforming Growth Factor beta1
Share to Blotting, Northern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to In Situ Hybridization

Share to Neoplasm Proteins

Share to Pancreatic Neoplasms

Share to Smad4 Protein

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 12379307
DOI: 10.1016/s0925-4439(02)00052-2

Genes

TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction and expression of betaig-h3 in pancreatic cancer cells.PMID 12379307Read ↗

Transforming Growth Factor-Beta-Induced Protein (TGFBI)/(βig-H3): A Matrix Protein with Dual Functions in Ovarian CancerSemantic proximity Read ↗

TGFBIp/betaig-h3 protein: a versatile matrix molecule induced by TGF-beta.Semantic proximity Read ↗

cDNA Cloning and Sequence Analysis of βig-h3, a Novel Gene Induced in a Human Adenocarcinoma Cell Line after Treatment with Transforming Growth Factor-βSemantic proximity Read ↗

TGFBI (βIG-H3) is a diabetes-risk gene based on mouse and human genetic studies.Semantic proximity Read ↗

Fibroblasts from non-healing human chronic wounds show decreased expression of βig-h3, a TGF-β inducible proteinSemantic proximity Read ↗

Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene.Semantic proximity Read ↗

Targets of Transcriptional Regulation by Transforming Growth Factor‐β: Expression Profile Analysis Using Oligonucleotide ArraysSemantic proximity Read ↗

Loss of Betaig-h3 protein is frequent in primary lung carcinoma and related to tumorigenic phenotype in lung cancer cells.Semantic proximity Read ↗

Downregulation of Betaig-h3 gene is causally linked to tumorigenic phenotype in asbestos treated immortalized human bronchial epithelial cells.Semantic proximity Read ↗

Epigenetic Inactivation of <i>Betaig-h3</i> Gene in Human Cancer CellsSemantic proximity Read ↗

Anterior segment dysgenesis after overexpression of transforming growth factor-beta-induced gene, beta igh3, in the mouse eye.Semantic proximity Read ↗

Type XIII collagen expression is induced during malignant transformation in various epithelial and mesenchymal tumours.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.