Article
Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer.
Carcinogenesis - 1 Oct 2002
Muto Manabu, Nakane Mari, Hitomi Yoshiaki, Yoshida Shigeru, Sasaki Satoshi, Ohtsu Atsushi, Yoshida Shigeaki, Ebihara Satoshi, Esumi Hiroyasu
Abstract excerpt
Patients with squamous-cell carcinoma in the head and neck (HNSCC) often develop second primary esophageal squamous-cell carcinomas (ESCC). In addition, widespread epithelial oncogenic alterations are also frequently observed in the esophagus and can be made visible as multiple Lugol-voiding lesi...
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