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Article

Immunity-Related Genes and Gene Families in <i>Anopheles gambiae</i>

3 Oct 2002

Abstract excerpt

We have identified 242 Anopheles gambiae genes from 18 gene families implicated in innate immunity and have detected marked diversification relative to Drosophila melanogaster. Immune-related gene families involved in recognition, signal modulation, and effector systems show a marked deficit of orthologs and excessive gene expansions, possibly reflecting selection pressures from different pathogens encountered in...

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PMID: 12364793
DOI: 10.1126/science.1077136

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