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Article

Molecular dynamics simulation of site-directed spin labeling: experimental validation in muscle fibers.

Biophysical journal - 1 Oct 2002

LaConte Leslie E W, Voelz Vincent, Nelson Wendy, Enz Michael, Thomas David D

Abstract excerpt

We have developed a computational molecular dynamics technique to simulate the motions of spin labels bound to the regulatory domain of scallop myosin. These calculations were then directly compared with site-directed spin labeling experimental results obtained by preparing seven single-cysteine mutants of the smooth muscle (chicken gizzard) myosin regulatory light chain and performing electron paramagnetic...

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Identifiers

PMID: 12324407
DOI: 10.1016/S0006-3495(02)73950-7
PMCID: PMC1302278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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