Article
The influences on human longevity by HUMTHO1.STR polymorphism (Tyrosine Hydroxylase gene). A relative risk approach.
Mechanisms of ageing and development - 1 Jul 2002
Tan Qihua, Bellizzi D, Rose G, Garasto S, Franceschi C, Kruse T, Vaupel J W, De Benedictis G, Yashin A I
Abstract excerpt
A new method based on the recently developed relative risk approach is introduced, and applied to data from Italian centenarian study (965 subjects aged from 13 to 109 years old) for investigating influences on longevity by Tyrosine Hydroxylase (TH) gene variability. The strategic parameterization enables the model to disentangle the various ways by which HUMTHO1.STR alleles (alleles 6, 7, 8, 9, 10*, 10, as...
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