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Article

Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002

Guan Xuen, Stege Justin, Kim Myoung, Dahmani Zina, Fan Nancy, Heifetz Peter, Barbas Carlos F, Briggs Steven P

Abstract excerpt

Zinc finger transcription factors (TFs(ZF)) were designed and applied to transgene and endogenous gene regulation in stably transformed plants. The target of the TFs(ZF) is the Arabidopsis gene APETALA3 (AP3), which encodes a transcription factor that determines floral organ identity. A zinc finger protein (ZFP) was designed to specifically bind to a region upstream of AP3. AP3 transcription was induced by...

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Identifiers

PMID: 12271125
DOI: 10.1073/pnas.192412899
PMCID: PMC130627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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