Article
Alteration of cell morphology and viability in a recA mutant of Streptococcus thermophilus upon induction of heat shock and nutrient starvation.
Gene - 24 Jul 2002
Giliberti Gabriele, Naclerio Gino, Martirani Luca, Ricca Ezio, De Felice Maurilio
Abstract excerpt
We identified the recA gene of the moderately thermophilic bacterium Streptococcus thermophilus and investigated the role of its product in the adaptation to heat shock and nutrient starvation. Expression of recA was required for optimal viability and normal cell morphology upon induction of both stresses. Normal induction of GroEL and ClpL in a recA knock-out mutant suggests that the RecA role in heat shock and...
Topics
- Anaerobiosis
- Bacterial Proteins
- Cell Division
- Chaperonin 60
- Electrophoresis, Polyacrylamide Gel
- Erythromycin
- Hot Temperature
- Microscopy, Electron, Scanning
- Molecular Chaperones
- Mutation