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Article

Multiple regulatory changes contribute to the evolution of the Caenorhabditis lin-48 ovo gene.

Genes & development - 15 Sept 2002

Wang Xiaodong, Chamberlin Helen M

Abstract excerpt

Recent work points to the importance of changes in gene expression patterns in species-specific differences. Here, we investigate the evolution of the nematode lin-48 ovo gene. lin-48 is expressed in several cells in both Caenorhabditis elegans and Caenorhabditis briggsae, but acts in the excretory duct cell only in C. elegans. We find the differences result both from alterations in the cis-regulatory sequences...

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PMID: 12231624
DOI: 10.1101/gad.996302
PMCID: PMC187439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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