Article
Variation in the expression of a Plasmodium falciparum protein family implicated in erythrocyte invasion.
Infection and immunity - 1 Oct 2002
Taylor Helen M, Grainger Munira, Holder Anthony A
Abstract excerpt
The PfRH protein family of Plasmodium falciparum is implicated in erythrocyte invasion. Here we report variations in the sequence, transcription, and protein expression of four different members of this family in three parasite lines, 3D7, T996, and FCB1. There are sequence polymorphisms in PfRH1, PfRH2a, PfRH2b, and PfRH3, ranging from variations across repeat regions to a 585-bp deletion in the 3' end of PfRH2b...
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