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Article

An analysis of BIGH3 mutations in patients with corneal dystrophies in the Kyushu district of Japan.

Japanese journal of ophthalmology - 1 Jan 2000

Yoshida Shigeo, Kumano Yuji, Yoshida Ayako, Hisatomi Toshio, Matsui Hiroyasu, Nishida Teruo, Ishibashi Tatsuro, Matsui Takao

Abstract excerpt

PURPOSE: To assess the involvement of BIGH3 in corneal dystrophies (CD) with an autosomal dominant trait, in patients referred to a hospital in the Kyushu district of Japan. METHODS: Forty-five CD patients from 44 families were studied. Genomic DNA was extracted from peripheral blood, and exons 4 and 12 of the BIGH3 gene were amplified by polymerase chain reaction followed by direct sequencing. RESULTS: In exon...

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PMID: 12225829
DOI: 10.1016/s0021-5155(02)00528-2

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ACD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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