Article
Inhibitors in the Swedish population with severe haemophilia A and B: a 20-year survey.
Acta paediatrica (Oslo, Norway : 1992) - 1 Jan 2002
Knobe K E, Sjörin E, Tengborn L I, Petrini P, Ljung R C R
Abstract excerpt
AIM: To survey the entire population (n = 116) afflicted with severe haemophilia A or B born in Sweden over a 20-y period (1980-1999), and to examine the epidemiological, genetic and clinical aspects of development of inhibitors to factors VIII and IX (FVIII/FIX). METHODS: One hundred of the subjects had haemophilia A and 16 had haemophilia B. All of these subjects had received prophylactic treatment and had a...
Topics
- Adolescent
- Child
- Child, Preschool
- Factor IX
- Factor VIII
- Genetic Predisposition to Disease
- Genotype
- Health Surveys
- Hemophilia A
- Hemophilia B
- Humans
- Incidence
- Infant
- Severity of Illness Index
- Sweden
- Time Factors
