Article
Single nucleotide polymorphism detection: allelic discrimination using TaqMan.
Psychiatric genetics - 1 Sept 2002
McGuigan Fiona E A, Ralston Stuart H
Abstract excerpt
Candidate gene studies are one of the most widely used approaches in the dissection of the genetic basis of disease. High-throughput methods for genotyping single nucleotide polymorphisms (SNPs) are necessary to perform large-scale association studies. We describe the use of the TaqMan or 5' nuclease allelic discrimination assay for genotyping polymorphisms of the collagen I alpha 1 (COLIA1) and vitamin D...
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