Article
L-carnitine reduces lymphocyte apoptosis and oxidant stress in HIV-1-infected subjects treated with zidovudine and didanosine.
Antioxidants & redox signaling - 1 Jun 2002
Moretti Sonia, Famularo Giuseppe, Marcellini Sonia, Boschini Antonio, Santini Gino, Trinchieri Vito, Lucci Luciano, Alesse Edoardo, De Simone Claudio
Abstract excerpt
Apoptosis is critical to the progression of human immunodeficiency virus-1 (HIV-1) infection. It appears reasonable that antiretroviral therapies may not achieve a full control of the infection in the absence of an impact on apoptosis. We assigned 20 asymptomatic HIV-infected subjects with advanced immunodeficiency to receive either zidovudine (AZT), and didanosine (DDI) or the same regimen plus L-carnitine, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.