Article
BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model.
International journal of cancer - 20 Sept 2002
Grizzle William E, Mountz John D, Yang Ping-Ar, Xu Xin, Sun Sheher, Van Zant Gary E, Williams Robert W, Hsu Hui-Chen, Zhang Huang-Ge
Abstract excerpt
To develop a better animal model for studying the effects of the host environment in neoplasia, we injected various genetically well-characterized H-2(d) RI strains of BXD mice with syngeneic breast cancer cells (TS/A) and monitored the growth of tumors over time. There was a marked difference in the growth of the implanted breast cancer cells among the 14 BXD RI strains, with 4 patterns of tumor development...
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