Article
Exclusion mapping of the genetic predisposition for cervical artery dissections by linkage analysis.
Annals of neurology - 1 Sept 2002
Grond-Ginsbach Caspar, Klima Bernhard, Weber Ralf, Striegel Johannes, Fischer Christine, Hacke Werner, Brandt Tobias, Hausser Ingrid
Abstract excerpt
Skin biopsies from a patient with a dissection of the left internal carotid artery and from four of his children were analyzed by electron microscopy. The index patient and three children showed mild but regular electron microscopic connective tissue aberrations. They were considered as carriers of an unknown autosomal dominant mutation. Thirty-four candidate genes involved in the biosynthesis of the...
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